MediMood

MediMood: A randomised controlled trial investigating the acute impact of a plant based Mediterranean-style dietary pattern (MDP) on mood, anxiety and cognition in UK adults with mild to moderate mental health complaints

Depression, anxiety and age-related cognitive decline are leading global public health problems. A Mediterranean-style diet promotes both physical and mental wellbeing and brain function in a long-term. As several underpinning biological mechanisms are likely to be responsive within hours or days, examining the short-term effect of a MDP on mental health outcomes is important.

MediMood aims to test whether a MDP can enhance mood, anxiety and cognition (brain function) following a meal (postprandial) and over 5-days in adults over 18 years with mild to moderate mental health problems (low mood and anxiety). We will conduct several computer-based tests measuring mood, anxiety and cognitive performance over the five days, brain imaging (MRI), and collection and analyses of blood, urine and faecal samples will also be carried out.

We believe the findings will have wide public health application because low mood, anxiety and stress disorders affect daily functioning and reduce the quality of life significantly for many.

If you would like to participate or know more, please email medimood@uea.ac.uk .

* Esgunoglu, L., Jennings, A., Connole, E., Murphy, K., & Minihane, A. (2022). Short-term effects of a Mediterranean-style dietary pattern on cognition and mental well-being: A systematic review of clinical trials. British Journal of Nutrition, 128(7), 1247-1256. doi:10.1017/S0007114521002567